Description

Concentration

• 10 mg per vial

Physical Form

• White lyophilized powder (sterile 3 mL vial)

Product Features

• Freeze-dried for maximal shelf stability
• Butyl rubber stopper allows multiple punctures while maintaining a secure seal
• Vials are depyrogenated and ETO-sterilized
• Tamper-evident aluminum flip-top for added protection

Peptide Structure & Registry

• Sequence: YE-Aib-GTFTSDYSI-Aib-LDKIAQ-(C20 fatty acid)-AFVQWLIAGGPSSGAPPPS
  • Aib = α-aminoisobutyric acid (non-proteinogenic)
• Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈
• Molecular Weight: 4 813.5 g/mol
• CAS Number: 2023788-19-2
• Synonyms / Codes: P1206 · LY3298176 · PubChem SID 156588324

Research Highlights

Robust & Durable Weight Reduction

• In long-term trials, GLP-2 10 mg produced ~19 % average body-weight loss over three years, with minimal regain in most subjects.

Glycemic Control & Insulin Sensitivity

• Dual activation of GIP and GLP-1 receptors lowers fasting glucose and enhances β-cell responsiveness, while boosting adiponectin levels (~26 % rise reported).

Cardiovascular & Renal Support

• Clinical data show ~38 % relative risk reduction in cardiovascular death or heart-failure hospitalization, alongside favorable kidney-function markers.

Real-World Flexibility

• Observational studies reveal ~12 % weight loss at six months even with slower dose-escalation; majority of participants achieve benefit at ≤10 mg.

Safety Profile

• Meta-analyses report no elevation—and a slight numerical reduction—in overall cancer risk versus placebo at the 10 mg dose.

Mechanism of Action (Simplified)

1. GIP R Agonism – Enhances insulin secretion and curbs appetite signals from the gut.
2. GLP-1 R Agonism – Delays gastric emptying, increases satiety, and contributes to cardioprotection.
3. Fatty-Acid Acylation – Albumin binding extends half-life, allowing convenient once-weekly administration in research models.

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Important Terms

For research use only (RUO). Not intended for human consumption or for use in medical, veterinary, or household applications. By purchasing this product, you agree to comply with all stated Terms & Conditions.